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human normal liver cell line lo2  (ATCC)
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ATCC human normal liver cell line lo2
Human Normal Liver Cell Line Lo2, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human normal liver cell line lo2 - by Bioz Stars, 2026-08
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human lo2 liver cell line  (Procell Inc)
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Procell Inc human lo2 liver cell line
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Human Lo2 Liver Cell Line, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human lo2 liver cell line - by Bioz Stars, 2026-08
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human normal liver cell line lo2  (China Center for Type Culture Collection)
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China Center for Type Culture Collection human normal liver cell line lo2
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Human Normal Liver Cell Line Lo2, supplied by China Center for Type Culture Collection, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lo2+human+liver+cells/l02+cell+line/pm39793400-37-2-9
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human normal liver cell line lo2 - by Bioz Stars, 2026-08
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human liver cell line (lo2)  (China Center for Type Culture Collection)
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China Center for Type Culture Collection human liver cell line (lo2)
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Human Liver Cell Line (Lo2), supplied by China Center for Type Culture Collection, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human liver cell line (lo2) - by Bioz Stars, 2026-08
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human liver immortalized cell line lo2  (BioResource International Inc)
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BioResource International Inc human liver immortalized cell line lo2
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Human Liver Immortalized Cell Line Lo2, supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human liver immortalized cell line lo2 - by Bioz Stars, 2026-08
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human normal liver cells (lo2  (Keygen Biotech)
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Keygen Biotech human normal liver cells (lo2
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Human Normal Liver Cells (Lo2, supplied by Keygen Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human normal liver cells (lo2 - by Bioz Stars, 2026-08
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human normal liver cell line lo2  (Ubigene Biosciences Co Ltd)
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Ubigene Biosciences Co Ltd human normal liver cell line lo2
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Human Normal Liver Cell Line Lo2, supplied by Ubigene Biosciences Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lo2+human+liver+cells/human+normal+liver+cell+line+lo2/pm39233275-45-66-78
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human normal liver cell line lo2 - by Bioz Stars, 2026-08
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lo2 human normal liver cell  (iCell Bioscience Inc)
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iCell Bioscience Inc lo2 human normal liver cell
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Lo2 Human Normal Liver Cell, supplied by iCell Bioscience Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human normal liver cells (lo2)  (ScienCell)
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ScienCell human normal liver cells (lo2)
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Human Normal Liver Cells (Lo2), supplied by ScienCell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lo2+human+liver+cells/human+normal+liver+cell+line+lo2/pm38668526-102-9-17
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human normal liver cells (lo2) - by Bioz Stars, 2026-08
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lo2 human normal liver cells  (iCell Bioscience Inc)
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iCell Bioscience Inc lo2 human normal liver cells
Impact of siNCOA4 on cellular responses in <t>LO2</t> cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.
Lo2 Human Normal Liver Cells, supplied by iCell Bioscience Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Impact of siNCOA4 on cellular responses in LO2 cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.

Journal: Scientific Reports

Article Title: HNF4A ameliorates acute liver failure by inhibiting NCOA4-mediated ferritinophagy

doi: 10.1038/s41598-025-13798-3

Figure Lengend Snippet: Impact of siNCOA4 on cellular responses in LO2 cells. A: NCOA4 mRNA expression in LO2 cells after siNCOA4 transfection (detected by RT-PCR); silencing efficiency was verified ( P < 0.01). B: NCOA4 protein expression in LO2 cells after siNCOA4 transfection (detected by Western Blot); silencing efficiency was confirmed ( P = 0.03). C: Cell viability in control, siNCOA4, LPS, and LPS + siNCOA4 groups (assessed by CCK-8 assay); siNCOA4 reversed LPS-induced viability reduction ( P = 0.020, one-way ANOVA). D: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); siNCOA4 alleviated LPS-induced mitochondrial deformation. E: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); siNCOA4 reduced LPS-induced Fe²⁺ accumulation ( P = 0.015, one-way ANOVA). F: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); siNCOA4 restored LPS-reduced membrane potential ( P = 0.018, one-way ANOVA). n = 5.

Article Snippet: The Human LO2 liver cell line (CL-0111, Procell Life Science & Technology Co., Ltd.) was maintained in RPMI-1640 medium (PM150110, Procell) supplemented with 10% fetal bovine serum (FBS, 164210-500, Gibco) and 1% penicillin/streptomycin (P/S, PB180120 , Procell) at 37 °C in a humidified atmosphere containing 5% CO2.

Techniques: Expressing, Transfection, Reverse Transcription Polymerase Chain Reaction, Western Blot, Control, CCK-8 Assay, Transmission Assay, Electron Microscopy, Staining, Membrane, Fluorescence

Cellular Impact of HNF4A Overexpression (oeHNF4A) in LO2 Cells. A: Cell viability in control, oeHNF4A, LPS, and LPS + oeHNF4A groups (assessed by CCK-8 assay); oeHNF4A reversed LPS-induced viability reduction ( P = 0.025, one-way ANOVA). B: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); oeHNF4A alleviated LPS-induced mitochondrial deformation. C: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); oeHNF4A reduced LPS-induced Fe²⁺ accumulation ( P = 0.017, one-way ANOVA). D: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); oeHNF4A restored LPS-reduced membrane potential ( P = 0.019, one-way ANOVA). n = 5.

Journal: Scientific Reports

Article Title: HNF4A ameliorates acute liver failure by inhibiting NCOA4-mediated ferritinophagy

doi: 10.1038/s41598-025-13798-3

Figure Lengend Snippet: Cellular Impact of HNF4A Overexpression (oeHNF4A) in LO2 Cells. A: Cell viability in control, oeHNF4A, LPS, and LPS + oeHNF4A groups (assessed by CCK-8 assay); oeHNF4A reversed LPS-induced viability reduction ( P = 0.025, one-way ANOVA). B: Mitochondrial morphology in each group (observed by transmission electron microscopy, scale bar: 10 μm); oeHNF4A alleviated LPS-induced mitochondrial deformation. C: Intracellular Fe²⁺ levels (detected by FerroOrange staining, scale bar: 100 μm); oeHNF4A reduced LPS-induced Fe²⁺ accumulation ( P = 0.017, one-way ANOVA). D: Mitochondrial membrane potential (assessed by JC-1 fluorescence, scale bar: 100 μm); oeHNF4A restored LPS-reduced membrane potential ( P = 0.019, one-way ANOVA). n = 5.

Article Snippet: The Human LO2 liver cell line (CL-0111, Procell Life Science & Technology Co., Ltd.) was maintained in RPMI-1640 medium (PM150110, Procell) supplemented with 10% fetal bovine serum (FBS, 164210-500, Gibco) and 1% penicillin/streptomycin (P/S, PB180120 , Procell) at 37 °C in a humidified atmosphere containing 5% CO2.

Techniques: Over Expression, Control, CCK-8 Assay, Transmission Assay, Electron Microscopy, Staining, Membrane, Fluorescence